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- O'ryan
- O-town
- O-zone
- O.a.r. (of A Revolution)
- Oak Ridge Boys
- Oasis
- Oathean
- Obie Trice
- Obituary
- Obliveon
- Oblivion
- Oblivion Dust
- Obsidian Gate
- Obtained Enslavement
- Obtest
- Ocean Colour Scene
- Oceans Of Sadness
- Oceansize
- October 31
- October Crisis
- October Fall
- Odd Project
- Odes Of Ecstasy
- Odious
- Odious Sanction
- Of Angels
- Of Montreal
- Of Sound And Fury
- Of The Son
- Of The Wand And The Moon
- Off By One
- Off Minor
- Off With Their Heads
- Office Of Strategic Influence (o.s.i.)
- Officer Negative
- Offset
- Offspring
- Oh, Sleeper
- Oi Polloi
- Oingo Boingo
- Oj Da Juiceman
- Ok Go
- Okkervil River
- Ol' Dirty Bastard
- Old (o.l.d.)
- Old 97's
- Old Dead Tree
- Old Man Gloom
- Old Man's Child
- Oleander
- Olive
- Oliver Magnum
- Olivia
- Olivia Lufkin
- Olivia Newton-john
- Olly Murs
- Omar A. Rodriguez-lopez
- Omarion
- Omd
- Omen